1. (adv.) In what manner or way; by what means or process.

2. (adv.) To what degree or extent, number or amount; in what proportion; by what measure or quality.

3. (adv.) For what reason; from what cause.

4. (adv.) In what state, condition, or plight.

5. (adv.) By what name, designation, or title.

6. (adv.) At what price; how dear.